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Life Sciences Fit Out Cost Guide

12/16/2025

Life Sciences Fit Out Costs: Insights for 2026

The 2026 U.S. Life Sciences Fit Out Cost Guide External Link provides a comprehensive analysis of fit out costs across nine lab subtypes in six major U.S. markets. With detailed cost breakdowns and market insights, this guide is an essential resource for capital planning and budgeting in the life sciences sector.

KEY TAKEAWAYS:

Construction costs are evolving. 
Fit out costs average $741 psf, reflecting a 2.9% YOY decrease due to lower fuel costs and competitive contractor bids.

Labor costs remain high. 
Persistent labor shortages and immigration policies continue to drive up skilled labor expenses, with wages rising 4%-5% YOY.

Pockets of activity persist. 
While overall construction has slowed, pharmaceutical manufacturing expansions and renovations of aging facilities are driving localized growth.

Leasing activity is rebounding. 
New leasing activity is up 31% since early 2024, signaling absorption of newly vacant spaces.

Life Sciences Fit Out Cost Guide
Our Life Sciences Fit Out Cost Guide covers five lab types, two cGMP types, warehouse and office across the six major U.S. life sciences markets.
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Authors

Brian Ungles St. Louis Project & Development Services
Brian Ungles

Executive Account Director, Global Occupier Services


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Jason D'Orlando (image)
Jason D'Orlando

Executive Managing Director, Project & Development Services
Raleigh, United States


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Sandy Romero New York Research
Sandy Romero

Head of Life Sciences & Healthcare Insights, Research Manager
New York, United States


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Maggie_Tillotson_headshot.jpg
Maggie Tillotson

Sr. Research Analyst
Indianapolis, United States


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CONTRIBUTORS

Ryan Ennis
Ryan Ennis

Sr. Managing Director, Life & Technology Science, Project & Development Services
Raleigh, United States


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kevin Camponeschi
Kevin Camponeschi

Managing Director, Americas Project Controls Lead
Baltimore, United States


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blake mcclellan
Blake McClellan

Sr. Director
Morrisville, United States


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Eric-Giles-Managing-Director
Eric Giles

Managing Director, Project & Development Services
Costa Mesa, United States


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Bill Hannula
Bill Hannula

Director, Life Sciences
Boston, United States


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